October 11, 2022, Virtual Meeting
Lia Gore, MD
Children’s Hospital Colorado, USA
Dr Lia Gore is a professor with tenure at the University of Colorado School of Medicine, and chief of pediatric hematology/oncology/bone marrow transplant-cellular therapeutics at Children’s Hospital Colorado and the University of Colorado School of Medicine. She received her medical degree from George Washington University School of Medicine and Health Sciences in Washington DC. She completed her internship in pediatrics at Children’s National Medical Center, and her pediatrics residency training and pediatric hematology/oncology fellowship and further postdoctoral training at the University of Colorado and Children’s Hospital Colorado.
Dr Gore’s research interests are focused on the development of novel cancer therapeutics, with an emphasis on pediatric and hematologic malignancies and improving access to clinical trials for children and adolescents. Her focus is on particularly high-risk diseases such as relapsed leukemia, sarcoma, and central nervous system tumors. She has been a principal investigator (PI) or co-investigator on more than 250 national and international clinical trials, including as the PI for trials leading to the approval of 4 drugs for childhood cancer.
Dr Gore serves on advisory panels of the Oncologic Drugs Advisory Committee to the US Food and Drug Administration, the Developmental Therapeutics and Department of Defense Study Sections of the National Institutes of Health, and has advised the European Medicines Agency on pediatric investigational plans for oncology products. She has directed a research study portfolio of over $30 million dollars. She is a founding co-director of the University of Colorado National Cancer Institute-designated Comprehensive Cancer Center’s hematologic malignancies program. Dr Gore currently serves as a co-director of the developmental therapeutics program, and on the executive committee for acute lymphoblastic leukemia. She is the groupwide vice chair for the Children’s Oncology Group.
Franco Locatelli, MD, PhD
University of Rome, IRCCS Ospedale Pediatrico, Bambino Gesù, Italy
Prof Franco Locatelli is head of the Department of Paediatric Haematology and Oncology, IRCCS Bambino Gesù Children’s Hospital in Rome, and full professor of pediatrics at the Sapienza University of Rome in Italy. He leads the largest program of childhood allogeneic hematopoietic stem cell transplantation (HSCT) in Italy and was recently appointed president of the Italian Higher Council of Health (Consiglio Superiore di Sanità), the technical scientific advisory body to the Ministry of Health. He graduated in medicine and surgery from the University of Pavia in Italy, where he also obtained a specialization in pediatrics and hematology. In 2005, he received the Gold Medal for Merit in public health by the president of the Italian Republic.
Prof Locatelli is an expert in childhood hematologic and oncologic malignancies. He was the president of the Italian Association for Pediatric Hematology-Oncology from 2004 to 2006, and served as chairman of the EWOG-MDS consortium from 2005 to 2011. Currently, he coordinates the national protocols for children with newly diagnosed acute myeloid leukemia and relapsed acute lymphoblastic leukemia. He has implemented in Italy the first-in-human academic studies on children with CD19+ lymphoid malignancies using second-generation retroviral chimeric antigen receptor (CAR) T cells and on children with GD2+ neuroblastoma.
Prof Locatelli is also involved in the development and validation of gene therapy approaches in patients with thalassemia and sickle cell disease and he has extensive experience in running phase I/II clinical trials. He is the author or co-author of 1,070 peer-reviewed articles published in international journals and he has an overall impact factor above 5000 and an H-index of 99 (Scopus source).